A bus carrying 50 people overturned in northern Mississippi on Wednesday afternoon, killing two on board, ABC News reported citing a local coroner.
According to ABC News, heavy sleet coated roadways in the area, which may have been a factor in Wednesday's accident.
Interstate 269 was closed in both directions near the site of the crash.
WREG-TV reported that 46 people were on board the bus at the time of the accident.
The bus was chartered in a route from Huntsville, Alabama to Tunica, Mississippi.